Cicero was hot on Xeno's tail when he was planning to hit Z'traa with the Vrai bioweapon before leaving the planet, and as such, followed him off the planet before it got nuked, but lost him immediately afterwards. Unable to return home, and her only family gone, she wandered the universe, honing her technical skills.
She later appeared in the middle of a fight between Ta'harok and Blackout when a chair somehow managed to throw her at Blackout. She appears to have hard feelings towards Blackout, seeing as he blew up her homeworld, after her brother nuked it.
- It appears that all of Xeno's family are whizzes with weaponry, as both he and his sister are quite good with them, Cicero being the elder, and better.