Spider-Man

Spider-Man is a superhuman crimefighter based out of New York, Earth.

History
Spider-Man fought the Green Goblin during his rise to power in an effort to prevent his killings. As a result, they became nemeses.

In 150,081 CMT, Rogue copied Spider-Man's power and used it to make puppets of the X-Men as an example of why Wolverine needed a curfew.

One of the reasons the Green Goblin wanted to join Mazkertis in his crusade was so that he could erase Spider-Man from the timeline of the Original Universe.